| Because of our location in the Texas Medical Center, our combined
years in practice, and our extensive experience, we are frequently
asked for consultative opinions by patients or by other physicians.
We are happy to provide this service for you. We can be most efficient
for you if you can provide your old records, or records pertaining
to your consult to us before or at the time of your consultation
visit. With your permission, we will send a letter communicating
our findings to your personal physician.
PAP SMEARS/DYSPLASIA
We are frequently consulted about the management of abnormal pap
smears, and find that many women have been advised to have surgical
procedures which may be unnecessary. Recent research indicates that
“watchful waiting” may be the most appropriate therapy, and surgery
may not be required. Also, when we determine that some form of surgery
is necessary, we are often able to give you the option of having
this done in our office rather than having to go into the hospital.
HYSTERECTOMY
Many patients want to know if their medical condition necessitates
hysterectomy. Obviously, each case must be evaluated on an individual
basis, and we will work with you to make the best decision. We may
determine that no surgery is required, or that a procedure named
endometrial ablation, which stops many problems with excessive uterine
bleeding, may be a reasonable alternative to hysterectomy. If we
determine that hysterectomy is required, it has often been our opinion
that what has been proposed to you as having to be done as an abdominal
case can in fact be done by us as a vaginal procedure. This will
result in less time in the hospital, less pain, faster recovery,
and no incision on the abdomen.
A new technology named focused high density ultrasound may also
be an alternative to hysterectomy for uterine fibroids.
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| The Pap smear was introduced to clinical medicine in
the early 1940's, and in the decades since, it has saved millions
of women's lives. The Greek physician, Dr. George Papinikalou, who
discovered the technique, realized that women who eventually developed
cancer of the cervix had pre-cancerous changes in the appearance of
their cervical cells that could be seen microscopically. Pap smear
technology involves scraping cells off of the surface of the cervix,
preserving them in a fixative solution, and then scanning hundreds
of individual cells to detect those that are pre-cancerous. Designed
as a screening tool, the pap smear still has the advantage of being
relatively inexpensive, easy and comparatively painless to obtain,
and sensitive in detecting the abnormal cells it is supposed to detect.
The beauty of the whole Pap concept is that we have a technique that
allows us to detect and treat abnormalities in the cervix before an
invasive cancer is present. However, it is not perfect.
Studies by epidemiologists eventually confirmed what had long been
suspected, that being that abnormal pap smears have a sexual origin.
Women who have never been sexually active do not develop abnormal
pap smears, or cancer of the cervix, and men transmit this virus
from one woman to another. In other words, cancer of the cervix
is actually a sexually transmitted disease. Further, we have discovered
that the maturing adolescent cervical cells are the most vulnerable
to infection by the human papilloma virus (HPV). Virgins do not
develop abnormal pap smears, and women in mutually monogamous relationships
will not be at risk.
We also know that being infected with HPV does not mean that disease
is bound to occur. Most women with an intact immune system will
eventually be able to eliminate this virus and its effects from
their bodies. However, not all will be able to, and this is partially
due to the particular virus causing the infection. Some viruses
are more aggressive than others, but we still do not know why some
women develop cancer and others do not. Having multiple sexual partners,
starting sexual activity at a younger age, and smoking are risk
factors for developing cancer.
Using DNA technology, we have broadly categorized HPV into two
types, those which are at "low risk" for inducing cancer, and those
that are at "high risk" for causing malignancy. The DNA science
will confirm whether the patient with an abnormal smear has been
infected with a low or high-risk virus, or whether she has even
been infected at all. Part of the imperfection in the Pap smear
is that it can be over-read, i.e., the suspicion that the smear
is abnormal is not confirmed if there is no HPV detected by DNA
testing. Minimally abnormal smears without proof of HPV infection
do not need further investigation or treatment.
With all of this relatively new information, the American College
of Obstetrics and Gynecology (ACOG) and several government agencies
have recommended that we consider changing the frequency with which
we obtain pap smears, or ask the laboratory to perform different
tests with the smear. We know that it takes about three years for
newly infected cervical cells to manifest themselves, so Pap smears
should commence three years after the onset of sexual activity,
and be repeated annually in young women. After age thirty, assuming
a mutually monogamous relationship (and that may be a huge assumption
in modern society), it may be satisfactory to obtain a Pap smear
combined with DNA testing every three years, rather than a Pap annually.
The problem with this ACOG approach is that many women equate the
"Pap smear" with "the annual gynecological exam", and many problems
we detect early with the annual exam, such as uterine fibroids,
ovarian masses, and breast problems will be delayed if patients
think they need to come only every third year for a Pap smear. Medicare
now will also pay for the Pap smear only every other year.
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Will you please do
the Ca-125 blood test for ovarian cancer?
Often (and incorrectly) described on the internet as "The Test Your
Doctor Doesn't Know About," the Ca-125 blood test is designed to
aid in the detection of ovarian cancer, and the lay press encourages
women to ask their physicians to obtain this test every year as
part of their gynecological exam. The fear that women have regarding
ovarian cancer is understandable-in 2002, there were about 23,000
cases in the U.S., and about 14,000 deaths, with the poor outcome
due primarily to the advanced stage of the disease present when
the diagnosis is made. Ovarian cancer is second in frequency only
to cancer of the uterine endometrium, and there are more deaths
from ovarian cancer than from the combination of cervical and uterine
cancer deaths.
However, this is not a silent cancer. Some 70% of women recall
having symptoms for 3 months before going to see their doctor, 35%
had symptoms for 6 months, and only 5% were asymptomatic. The best
method of detection is for both patient and physician to know the
presenting signs and symptoms, and to maintain a high index of suspicion
for this problem. The symptoms include abdominal bloating, an increase
in abdominal girth, abdominal and pelvic pain, inability to eat
normally (getting "full" too quickly),constipation, urinary frequency
(from pressure on the bladder), and unexplained weight loss. When
experiencing these symptoms, the gynecologist should perform a thorough
pelvic exam, and obtain imaging studies of the pelvis, such as an
ultrasound. In pre-menopausal women, the problem with the Ca-125
test is that it is exquisitely sensitive, but also quite non-specific.
This means that it can be falsely elevated due to common benign
conditions other than ovarian cancer, such as uterine fibroids,
pelvic infections, endometriosis, adenomyosis, pregnancy, and even
menstruation.
Additionally, the Ca-125 test is not always elevated in ovarian
cancer. About 50% of early stage cancers, and 25% of advanced malignancies
are associated with normal test values. In the largest study of
test accuracy, some 22,000 women were screened with the blood test,
and pelvic ultrasound if the blood test was elevated. 98% of the
enrollees had a normal blood test, and 41(0.1%) had elevated blood
test values and abnormal ultrasounds. These 41 patients were taken
to surgery, and only 11 of them (0.05% of all of the women screened),
had ovarian cancer. The false positive rate was 73% of those women
who had surgery.
Unfortunately, there is not yet a really good test for this frightening
pelvic malignancy. We do think it is appropriate when your symptoms
suggest that there may be a problem, or if you have a first-degree
relative (your mother or your sister) with a history of ovarian
cancer. For the present, however, we do not believe that this test
should be a "routine" part of every annual gynecological exam, and
if it were to be done with the frequency with which it is requested,
it would lead to a lot of unnecessary surgery, especially in the
pre-menopausal population.
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When Should My
Daughter Have Her First Visit to the Gynecologist?
The simple answer to this question is that she should be seen whenever
she has a significant gynecological problem. We are comfortable
seeing any age patient in our practice, and even infants can have
gynecological issues which merit the attention of a gynecologist.
However, the usual question is, "When does my teenage daughter need
to see a gynecologist for the first time"? In Health Care for
Adolescents, published by the American College of Obstetrics
and Gynecology in 2003, the suggestion is made that the initial
visit should be between the ages of 13 and 15. As ob/gyns, we are
comfortable providing primary care for the adolescent, or we will
be happy to work in a collaborative role as consultant to the adolescent's
primary health care physician. The initial visit does not necessarily
need to involve a pelvic exam, but instead it can be simply to establish
rapport and to serve as a question-and-answer session regarding
adolescent development, and a screening visit for common teen-age
eating disorders.
What Methods
of Contraception Are Available At Your Office?
- Prescriptions for birth control pills, including the progestin-only
pill suitable for use while breast-feeding.
- Prescriptions for the "morning after" pill.
- Prescriptions for birth control patches.
- Prescriptions for birth control vaginal rings.
- Prescriptions for diaphragms.
- Out-patient surgical procedures for permanent sterilization,
including laparoscopic bilateral tubal ligation, and the Essure
procedure, a hysteroscopic technique that blocks the tubes at
their entrance into the uterus.
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